Serrapeptase
Serrapeptase is an enzyme that was first discovered in the intestine of silkworms. This enzyme is necessary in order for the silkworm to dissolve the hard cocoon it is surrounded by, when it is ready to emerge as a moth. The silkworm also uses this enzyme to allow it to feed on tough mulberry leaves. These days, serrapeptase supplements are not derived from silkworms; the enzyme is derived from a natural fermentation process. Serrapeptase is a protease enzyme; that means it has the ability to digest protein. Research has shown this remarkable enzyme can help to dissolve non-living tissue in the body such as cysts, swellings, plaque and scar tissue.
Serrapeptase helps to reduce inflammation in the body
Excessive inflammation is a feature of just about every disease and is present in any condition where pain, fatigue and fluid retention are present. But what causes inflammation? These are the most common causes:
- Elevated blood sugar. Certainly diabetics experience a great deal of inflammation in their bodies because of elevated blood sugar, but you don’t have to be a diabetic to experience this. Regularly consuming sugar, grains and high glycemic load foods will flood your bloodstream with glucose. Sugar is sticky and it can bind to proteins in your body and damage them.
- Infections. Any type of bacterial, viral, fungal or parasitic infection raises inflammation because your immune cells produce massive quantities of inflammatory chemicals as they try to fight the infection. This is particularly a problem in chronic, long term infections.
- Food allergy, intolerance and sensitivity. Whenever you consume a food you are sensitive to, your body behaves as though you swallowed something harmful, such as a virus or bacteria. As your immune system tries to cope with this scenario, it produces a host of inflammatory chemicals. This can become a significant problem if you unknowingly eat this food(s) every day.
- Stress. Unfortunately the hormones your body produces while you are stressed cause inflammatory damage, free radical damage and a great deal of wear and tear to your body. Magnesium helps to counter some of this damage.
- Lack of sleep or poor quality sleep. Good solid sleep is one of the most powerful anti-inflammatory remedies there is, and it’s free and feels great. Unfortunately most people know this but try as they might, they can’t get good sleep consistently. Insomnia or just poor quality sleep is endemic in modern society.
- Lack of antioxidants in your diet. All of the various conditions listed above cause your body to use up vitamins, minerals and antioxidants at a much faster rate. The problem is, most people don’t replenish their bodies with nutrients sufficiently. Ideally you would consume a raw vegetable salad for lunch and dinner each day and include a glass of raw vegetable juice most days of the week.
- Injuries, accidents and surgery are a major physical stress on the body and these processes all generate a great volume of inflammatory chemicals. These inflammatory chemicals are very useful in acute conditions and are necessary for the recovery process. Unfortunately many patients are left with chronic pain, swelling and immobility because the inflammatory process has continued for too long. Serrapeptase is excellent for these people.
How Serrapeptase can help
Ideally you could reduce the level of inflammation in your body by addressing each of the points mentioned above. Unfortunately, this is not always possible and sometimes the source of inflammation cannot be identified and remains hidden.
Serrapeptase basically works by giving your insides a good clean up. Being a protein digesting enzyme, it helps to clear out protein deposits that are not serving a useful purpose in your body. It has anti-inflammatory, anti-oedemic (reduces fluid retention) and fibrinolytic activity (helps to break down blood clots). It can help to clear mucus, fluid, blood clots, debris and immune complexes from your body. In this way it helps to reduce pain, improve mobility and increase energy. Serrapeptase helps to keep arteries clean and clear because it reduces the inflammation in arteries which is what promotes cholesterol accumulation and narrowing of the arteries.
How should Serrapeptase be taken?
Serrapeptase must be taken on an empty stomach in order to obtain the systemic anti-inflammatory benefits. If you consume it with a meal, your body will use it to digest the food in your intestines. Therefore most people find it easiest to take serrapeptase first thing in the morning. You can eat half an hour later. A typical starting dose is between 125 000 and 250 000 IU per day.
The above statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease.
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I was diagnosed with Polymyalgia Rheumatica (PMR) 3 months ago. My doctor put me on 15mg Prednisone. I dont like taking steroids due to the side affects so am taking natural supplements that will help my immune system and support my adrenal glands. With the help of my Doctor I am now on 7mg on Prednisone but unfortunateyly some of the symptoms have returned. I expected this to happen as I know PMR can take many months to clear. I have just started taking Serrapeptase to reduce the inflamation but am having difficulty working out when best to take it - especially as one of the supplements that will help improve my immune system has to also be taken on an empty stomach. Current dosage is 2x125,000iu 3 times a day. I am going for a high dose as I hope to quickly reduce some of the symptoms so that I can taperthe prednisone by 1mg every 2/3 weeks. Can you please advise whether it can be just as beneficial to take 2 or 3 tablets twice daily instead of 2 3 times daily. Any advice would be gratefully received
Thank you for your comment.
Serrapeptase will work best when taken away from food. Whenever you are able to fit it in around your eating schedule is fine.
If you would prefer to take 3 caps twice daily instead that should be fine. Just start on a lower dose and build up to a higher dose as some people experience stomach upset from Serrapeptase.
Kind regards,
Louise
Yes serrapaptase would be excellent for you to take. Please discuss with your doctor first if you are taking a blood thinner.
Kind regards,
Louise
So should I avoid a curtain vitamin or is it fine ? And does constipation effect the absorption of serrapeptase?, Thanks
You just have to be careful taking serrapeptase with other supplements that have blood thinning effects like fish oil and vitamin E.
It really depends on the dose of what you are taking, and also your unique constitution as to whether they may thin your blood excessively. Bruising and nose bleeds are indicators of excessive blood thinning.
Kind regards,
Louise
Yes serrapeptase is safe but stick to one capsule daily on an empty stomach.
Kind regards,
Margaret
Breaks from serrapeptase are not required. Most of our patients have long term inflammatory conditions, and it helps to keep inflammation down.
We are not aware of studies of its long term use.
For benign cystic breasts we recommend 1 capsule twice daily on an empty stomach. Selenium, iodine and vitamin D are also very helpful. They are combined in Breast Health capsules:https://www.liverdoctor.com/breast-health-60-capsules.html
Kind regards,
Louise
Our serrapeptase supplement contains 125,000 spu per capsule. If you purchased a different brand you would need to contact that company directly to check the conversion. Generally speaking 10mg = 20,000 spu.
Kind regards,
Louise
So Should I avoid all these as they do thin blood:
-turmeric
-bromelain
- Vitamin e
- fish oil
- ginger, garlic
- cordyceps
- Boswellia
-vitamin k2mk7
Thanks for the response in advance , I have spoken to my doctor who didn’t even know what serapeptase was.
It's always good to check.
All of the things you listed can be taken with serrapeptase. Fish oil, garlic and vitamin E are the strongest blood thinners. It really depends on the dose of all those things you are taking, and also your unique constitution as to whether they may thin your blood excessively. Bruising and nose bleeds are indicators of excessive blood thinning.
Kind regards,
Margaret
Yes, that is appropriate. If HBP is high blood pressure, magnesium is also very helpful.
Kind regards,
Margaret
Vomiting is not an expected side effect of Serrapeptase.
Try starting with one capsule of Serrapeptase daily and see how you react. If you can tolerate this, after a few days increase to one capsules twice daily and work your way up to a higher dose.
If you experience vomiting again cease use. You can call our office and speak with our naturopath Christine on +1 (623) 334-3232.
You might benefit from also supplementing with Glutamine to soothe and heal the gut lining:https://www.liverdoctor.com/glutamine-plus-colostrum-powder-500grams.html
Kind regards,
Louise
It is not recommended to take them both together because of the blood thinning effects.
It is always best to check with your own doctor.
Kind regard,
Louise
I have had the same reaction as William when taking serrapeptase. The first time I took before bed on an empty stomach and then felt sick all the next day. I took courage a week later but took 2 hours before breakfast, 30 minutes after breakfast I had fever, severe vomiting and severe Diarrhoea. I was at work at the time and it was several hours before I could even drive home. The sickness and Diarrhoea happened every 10 minutes. Have since recovered but am scared to take serrapeptase again, I am trying to get rid of bursitis in my left hip which is very painful at night and I don't sleep well. any advice would be appreciated.
thanks
Gaynor
It is such a shame that you have reacted so severely to Serrapeptase.
Another plan of action is to take active steps to reduce inflammation in your body and the first place to look is the digestive tract because this is where most inflammation begins.
We recommend you begin an anti-inflammatory diet and lifestyle, and we are delighted to let you know that Dr Cabot’s highly acclaimed 15 Day Cleanse is available and provides you with two weeks to begin your journey toward improved overall health and function, utilising both supplements and a tasty, easy to prepare dietary regimen. This is an anti-inflammatory program and the supplements are immune boosting, body alkalinising and gut healing.https://www.liverdoctor.com/15-day-cleanse.html
After completing the Cleanse, we recommend you remain on this style of eating and you can then begin the Maintenance plan.https://www.liverdoctor.com/dr-cabot-ultimate-maintenance-plan.html
To further reduce inflammation and aid healing, Dr Cabot prescribes
N-Acetyl-Cysteine (NAC 600mg) – 1 to 2 capsules twice daily well away from food with a large glass of water, if any upset occurs, take at the beginning of your meals. This supplement works well with Livatone Plus to get your liver better faster. This supplement is the precursor nutrient of glutathione; the body’s strongest anti-oxidant and potent detoxifier.https://www.liverdoctor.com/nac-n-acetyl-l-cysteine-600mg-90-capsules.html
Collagen Food – ½ teaspoon in water twice daily. Formulated to promote collagen production boost immune function and reduce inflammation.https://www.liverdoctor.com/collagen-food-200g.html
You may purchase these supplements and Dr Cabot’s books athttps://shop.liverdoctor.com/
Kind regards,
Victoria Taylor BHSc
Naturopath
Serrapeptase does thin the blood. In some people that can produce excessive bruising. Maybe the one bruise is unrelated and something you did while sleeping. If more bruises appear you may need to reduce your dose.
Kind regards,
Margaret
Recently I took it and it made me feel nauseated. So I didn't take it again for several weeks. When I took it again - in the morning on an empty stomach as always - i was gripped by horrible pain and vomiting. I had no food in my stomach but I threw up everything my body could squeeze out for nearly 3 hours.
Any idea why this would suddenly impact me this way? I am so bummed but I don t think I can ever take this again.
This is a very unusual response. It is best to see your doctor and maybe a gastroenterologist as well. There could be inflammation in your digestive lining.
Kind regards,
Margaret
Does Serapeptase help reduce cholesterol and can it cure carpel tunnel? Please advise on dosage and if it can be taken with iron supplements, B vitamins, magnesium? (At same or different times of the day)
Kind regards
Suzanne
Serrapeptase can be taken with all those supplements but it’s best on an empty stomach and they are best with food. It helps to reduce cholesterol deposits in arteries, but berberine is better for reducing overall cholesterol levels-https://www.liverdoctor.com/berberine-500mg-60ct.html
Serrapeptase has helped carpel tunnel for many of our patients. A good dose would be 1 capsule twice daily on an empty stomach.
Kind regards,
Margaret
I can't seem to find serrapeptase on your site to buy? Where would it be? Thanks
Veronica
You can purchase it here:
https://www.liverdoctor.com/serrapeptase-250-000-iu-per-two-caps.html
Kind regards,
Louise
Serrapeptase works best on an empty stomach. When taken with food it will not work as well. If you can tolerate it hours before a meal then this would be fine to do so. Some people get an upset stomach from serrapeptase and may need to take it closer to food.
Kind regards,
Louise
Can I take serrapeptase and vitex together?
It helps reduce inflammation and that seems to have helped your thyroid gland. Lowering the dosage means your thyroid is able to manufacture more hormones.
Kind regards,
Margaret
What would you recommend, i have pcos and one blocked felopian tube. Been ttc for almost 10years and no luck.
Thank you for your enquiry.
PCOS makes conception more difficult and having one tube blocked also reduces your chances.
We recommend a low carb, anti-inflammatory diet for PCOS and Dr Cabot prescribes her 15 Day Cleanse to begin the process, and the Maintenance Plan to continue as a long term strategy.
Serrapeptase is well indicated to clear your fallopian tube. You may find the Cleanse style diet will make this happen quicker.
Kind regards
Victoria Taylor
Naturopath
Is it safe to take folic acid supplements with Serrapeptase( korzin)
There are no known interactions between folic acid and Serrapeptase.
Kind regards,
Louise
Does it causes constipation or leaving it causes constipation
Constipation is not a common symptom on Serrapeptase.
Are you currently taking it and experiencing constipation?
If so - Every one is unique and reacts to things differently. We suggest stopping Serrapeptase until the constipation resolves, and then start taking it again and see if you get constipated again.
Ensure you are drinking plenty of water.
Kind regards,
Louise
Are you referring to inflammation showing up in blood tests?
Kind regards,
Louise
Serrapeptase can reduce inflammation which may result in cartilage loss. Take 1 capsule twice daily on an empty stomach. MSM (sulfur), vitamin C and gelatin all help the body to manufacture cartilage, helping to maintain your levels for longer.
Kind regards,
Margaret
With serrapeptase try one capsule twice daily on an empty stomach. Selenium, zinc and vitamin D all help the body fight infections. D-mannitol can help clear infections from the bladder.
Kind regards,
Margaret
Thank you
Yes, serrapeptase should help reduce scarring and inflammation. The dose is 1 capsule twice daily on an empty stomach. Vitamin E helps reduce scarring, and Livatone Plus help protect liver cells from damage and can help reduce the progression of cirrhosis.
Kind regards,
Margaret
We don’t have experience with serrapeptase for vulval cysts. It may help. Vitamin D and selenium should help, along with a dairy and sugar free diet.
Kind regards,
Margaret
2 capsules three times daily, 15 minutes before food with a whole glass of water for 6 weeks, then reduce to 2 capsules twice daily
Also take vitamin E natural form 1,000 IU daily with food and vitamin C 2,000mg daily
Also take Selenomune one capsule daily with food
Try to exercise regularly and keep your weight in the healthy range
Kind regards,
Dr Sandra Cabot
2 capsules twice daily, 15 minutes before food with a whole glass of water
Super Vitamin K, 2 capsules daily with food
Magnesium Ultrapotent powder one teaspoon daily in water
Good results should be seen after 2 to 4 months, depending upon severity
Physiotherapy is also important treatment
Kind regards,
Dr Sandra Cabot
Does Serrapeptase make you loose weight?
Will Serrapeptase get rid of massive raised keloid scars?
Serrapeptase is not specific for weight loss. We have not seen it remove keloid scars.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
I hope you're well! I have a question regarding serrapeptase please; I am unable to swallow capsules or tablets and I'm wondering if I will receive any benefit at all if I was to empty the capsule into some liquid and drink the liquid down. I know it is suppose to stay coated through the stomach but I cannot think of any other way and really want the benefit of serrapeptase.
Thanks so much for your time. Warmest regards.
Yes, you should certainly still experience the benefits of serrapeptase. We have several customers who do this.
Kind regards,
Margaret Jasinsnka
Naturopath for Liverdoctor.com
I’ve had keloids on my shoulders chest and back for the past 4 years. I purchased Serrapeptase 40,000 SPU and I’m currently taking one pill in the morning and one at night. Is it too much/not enough? Also, is it okay for me to take it along with other medication such as Thyrofix (thyroid) and birth control pill?
Thanks
The dose you are taking is appropriate and serrapeptase is fine with your medication.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
It’s fine to drink tea with serrapeptase. Serrapeptase is a protein-digesting enzyme, so it’s best not to have protein-containing foods in your stomach while taking it.
If you take serrapeptase capsules on an empty stomach, they will be absorbed after roughly half an hour, so it is fine to eat after that.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Can serrapeptase help with removing fibroids and opening of the Fallopian tubes. I have been taking 250,000 serrapeptase 1 tablet per day before breakfast, will it help open the tubes and stop the fibroids from growing. I had surgery 2 years ago to remove several fibroids and I don’t want them to grow back.
I also have pain on one of my shoulder which extends to my biceps and I have been referred to physio, can serrapeptase heal this pain.
Thanks for your help.
We do not have experience with the use of serrapeptase for uterine fibroids or blocked fallopian tubes. Vitamin D, FemmePhase capsules and flushing the fallopian tubes with poppy seed oil may help. Serrapeptase is very likely to help relieve the pain in your shoulder. Try taking 2 capsules daily on an empty stomach.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
This is not likely to be related to serrapeptase. It is not a weight loss supplement.
It is best to see your doctor for a blood test.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Thank you for your comment. This procedure would need to be performed for you by your doctor.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Thank you in advance for your dosage and treatment recommendations!!
It is common for the capsule around silicone implants to harden and this can be painful.
Serrapeptase is safe to take and worth trying.
Sometimes it is safer to have the implants removed.
Please see our book The Breast Cancer Prevention Guide:https://www.liverdoctor.com/products/books/breast-cancer-prevention-guide.html
Kind regards,
Dr Sandra Cabot
Serrapeptase will reduce scar tissue – take one three times daily 10 minutes before food with glass of water.
It will have a gradual effect and need to take it for 2 months
I cannot say how long it will take because I do not know the extent of the surgery. Was a cancer on the lip? Was it the whole lip or just part of the lip?
Kind regards,
Dr Sandra Cabot
also take vitamin C 1000mg daily
eat one avocado daily for extra vitamin E
Dr Cabot
I started serrapeptase about a month ago, hoping to clear up small amounts of mucus and for general lung health. I’m having two itchy, kind of blistery bumps break out on my right leg and one on my left hand; also small bumps on the margin of my jaws. Could this be related to the serrapeptase? I’d like to keep taking it for the benefits. Please advise. Thank you!
This is not a typical reaction. Perhaps it’s an allergic reaction or perhaps it is not related and just a coincidence.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
I have -
At C5/6 & C6/7 are broadbased disc osteophyte complexes, larger on the right. These both cause relatively severe narrowing at the right exiting foramina and encroachment upon the exiting right C6 & C7 nerve roots. The degree of narrowing is severe at right C7 nerve root.
Will serrapeptase eliminate osteophyte's?
Thanks in advance,
Serrapeptase probably won’t help. Vitamin K2 should help though. It assists with getting calcium into bones and away from deposits in other parts of the body.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Yes serrapeptase can be taken long term as a natural way to keep arteries clear and keep levels of inflammation in the body low.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
We don’t have experience with topical serrapeptase. It may not be absorbed into the skin well, as it is an enzyme.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
No, unfortunately we are not aware of any benefits it would have for varices.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Questions is - is it too soon to be taking Serra after the recent fall? I'm healing well though there is an obvious weakness in the area.
Thank you,
Andy
If the fall was several weeks ago, it is appropriate to start taking serrapeptase now.
MSM Plus Vitamin C powder would help with healing because it promotes collagen production.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Serrapeptase can aggravate ulcers or inflammation in the stomach or intestines. Ideally healing your digestion so you can tolerate the serrapeptase is key. Glutamine and the other ingredients in Gut Health powder help with this. So does a gluten, dairy and sugar free diet.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Serrapeptase can probably reduce the amount of scar tissue, but it seems like you are one of those people who genetically produce excess scar tissue. Most people can take 2 capsules twice daily. Taking high doses of serrapeptase can thin the blood excessively in some people and they experience nose bleeds or bruising.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
It would be good to take 120,000 units daily. It is best taken on an empty stomach.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Thank you for your comment. We don’t have patient experience with someone in your mother’s position, but it is worth trying, with her doctor’s approval.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
We don’t have patient experience with serrapeptase and emphysema and are not aware of research showing it to be beneficial.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Can I take serrapeptase with blood pressure medicine?
Thanks
Yes, that is fine.
Kind regards,
Margaret Jasinska
Naturopath for Liverdoctor.com
Serrapeptase or nattokinase are unlikely to dissolve all the scar tissue, but they may reduce some. Nerve cells can die due to lack of blood supply.
Some research has shown that a ketogenic diet and exogenous ketones can assist with nerve repair.
Best wishes
Margaret Jasinska ND